SILVER: An efficient tool for stable isotope labeling LC-MS data quantitative analysis with quality control methods
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SILVER is an efficient tool for quantification of the stable isotope labeling mass spectrometry data. SILVER implements novel methods for quality control of quantification at spectrum, peptide and protein levels respectively. Several new confidence filters and indices are applied to improve the accuracy of quantification results. Additionally, SILVER provides user-friendly interfaces for parameter setting, quantitative analysis, result visualization and manual validation as well as some useful statistics analyses.

The core of SILVER was developed on the platform of Microsoft Visual C++ 2005 in Windows system. SILVER can be run directly on any Windows system (Windows 7/Vista/XP/2003/2000, 64 bit version or 32 bit version). And the interfaces of SILVER was implemented in Java.

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